Awareness * Advocacy * Research

Histamine Intolerance

Histamine intolerance is the intolerance towards “normal” levels of histamine in food caused by a decreased activity of the histamine-degrading enzymes diamine oxidase (DAO – degrades in the gut) or histamine N-methyltransferase (HNMT – which degrades histamine in the skin and brain).

Because of the multifaceted nature of the symptoms, the existence of histamine intolerance has been underestimated.

Link to external websites for further research:
National Institutes of Health – Histamine Intolerance
NIH – Pseudo Allergies are Linked to Histamine Intolerance
NIH – Importance of a Histamine Free Diet
Histamine Intolerance Information
A Visual Guide to Histamine Intolerance (What to and not to eat).
Genetic Connection Histamine Intolerance, MTHFR, Methylation
Facebook Support Group
The Low Histamine Chef

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Nuggets of Wisdom

Yes, there is such a thing as having an allergic type reaction to temperatures. This is defined as a physical urticaria. Other physical urticarias include Solar, Aquagenic, Pressure, Vibration and Exercise.

Most reactions are pseudo-allergic. By definition, an allergy involves inhaling or consuming an allergen. Physical urticarias have no known allergen. Despite the terminology and medical definitions, systemic reactions can be life threatening.

Cold has an arbitrary definition based on an individual feeling. For a person with a cold urticaria, cold can be defined as any temperature cooler than their own body temperature.

You do not have to be cold to have a reaction to the cold; contact with cold can trigger a reaction.

You can have an allergic type reaction to both cold and heat simultaneously.

Most reactions considered anaphylactic are really anaphylactoid by definition.

Moving to a warmer climate as a treatment for Cold Urticaria is a myth. Warmer climates present their own issues for those with Cold Urticaria.

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