Awareness * Advocacy * Research

Injectable Epinephrine

Recognize the symptoms that might occur.
Anaphylaxis is a potentially life‑threatening reaction that can occur within seconds of exposure to cold.  It is important to know that Epinephrine is the only approved first line of treatment for Anaphylaxis.  Anytime Anaphylaxis is recognized, the individual should immediately have Epinephrine administered and follow up with either the physician or at an emergency room. It is often difficult to rationalize when the right time is to use an auto-injector. The severity of symptoms is not always obvious.  Some doctors recommending using the rule of thumb that when three or more body systems are affected, it is time to administer a dose of Epinephrine.  Talk to your doctor about what is right for you.

Body systems affected and recognized symptoms.

Anaphylaxis Symptoms

Link to external websites for further research:
Vero doctor publishes life-saving anaphylaxis research
Injectable Epinephrine: An Epidemic of Misuse
Epi-pen Zero Co-Pay
Anaphylactic reactions can have rebound effect

Nuggets of Wisdom

Yes, there is such a thing as having an allergic type reaction to temperatures. This is defined as a physical urticaria. Other physical urticarias include Solar, Aquagenic, Pressure, Vibration and Exercise.

Most reactions are pseudo-allergic. By definition, an allergy involves inhaling or consuming an allergen. Physical urticarias have no known allergen. Despite the terminology and medical definitions, systemic reactions can be life threatening.

Cold has an arbitrary definition based on an individual feeling. For a person with a cold urticaria, cold can be defined as any temperature cooler than their own body temperature.

You do not have to be cold to have a reaction to the cold; contact with cold can trigger a reaction.

You can have an allergic type reaction to both cold and heat simultaneously.

Most reactions considered anaphylactic are really anaphylactoid by definition.

Moving to a warmer climate as a treatment for Cold Urticaria is a myth. Warmer climates present their own issues for those with Cold Urticaria.

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