Awareness * Advocacy * Research

Delayed Cold Induced Urticaria is a delayed cutaneous response to cold, characterized by areas of itchy, red, fluid filled deep swelling at 9 to 18 hours following cold exposure and can resolve into hyperpigmented spots. Cold Stimulation Timed TestsĀ are immediately negative, but reactions occur several hours later at the site of testing.

The delayed cutaneous response to cold can not be passively transferred with serum or tissue in blood transfusions. Family studies suggested an autosomal-dominant mode of inheritance.

Links to external websites for further research:
Delayed Cold Urticaria
Familial Atypical Cold Urticaria: Description of a New Hereditary Disease

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Nuggets of Wisdom

Yes, there is such a thing as having an allergic type reaction to temperatures. This is defined as a physical urticaria. Other physical urticarias include Solar, Aquagenic, Pressure, Vibration and Exercise.

Most reactions are pseudo-allergic. By definition, an allergy involves inhaling or consuming an allergen. Physical urticarias have no known allergen. Despite the terminology and medical definitions, systemic reactions can be life threatening.

Cold has an arbitrary definition based on an individual feeling. For a person with a cold urticaria, cold can be defined as any temperature cooler than their own body temperature.

You do not have to be cold to have a reaction to the cold; contact with cold can trigger a reaction.

You can have an allergic type reaction to both cold and heat simultaneously.

Most reactions considered anaphylactic are really anaphylactoid by definition.

Moving to a warmer climate as a treatment for Cold Urticaria is a myth. Warmer climates present their own issues for those with Cold Urticaria.

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