Delayed Cold Induced Urticaria is a delayed cutaneous response to cold, characterized by areas of itchy, red, fluid filled deep swelling at 9 to 18 hours following cold exposure and can resolve into hyperpigmented spots. Cold Stimulation Timed Tests are immediately negative, but reactions occur several hours later at the site of testing.
The delayed cutaneous response to cold can not be passively transferred with serum or tissue in blood transfusions. Family studies suggested an autosomal-dominant mode of inheritance.
Links to external websites for further research:
Delayed Cold Urticaria
Familial Atypical Cold Urticaria: Description of a New Hereditary Disease